Ann Vincent-Salomon, MD, PhD

Institut Curie , France

 

Anne Vincent-Salomon is pathologist, MD, PhD, head of the department of pathology-genetics and immunology, practicing at the Institut Curie since 1993. She has an MD degree from the University Paris VI and a PhD degree in Cellular and Molecular Genetics from Paris Sud University. Her domains of expertise are breast pathology, surgical pathology, and hematopathology. Her deep commitment for breast pathology strongly motivated her willing to reinforce the breast tumor characterization using immunohistochemistry as well as molecular tools. From 2003 to 2013, she was granted twice successively by the INSERM that enabled her to achieve her PhD thesis in Dr. Delattre’s laboratory (INSERM U830). One of the first achievements in her scientific career was the identification and validation of a DNA based-prognostic signature for early small luminal HER2-neg breast carcinoma patients (Gravier et al, 2010; Vincent-Salomon et al, 2013). From then, she pursued and extended her main domain of research interest in breast carcinoma genomics with a special focus on the heterogeneity of basal-like breast carcinomas and ductal carcinomas in situ. During the last few years, her research activities aimed at better characterizing histological special subtypes of breast cancer in order to contribute to breast cancer taxonomy, which is important for prognostic and diagnostic purposes. In particular, she investigated the phenotypic/morphological characteristics of breast cancers such as lobular tumors, rare types of invasive tumors including metaplastic, medullary and micropapillary carcinomas, and ductal carcinomas in situ. Since January 2014, she joined the U934 INSERM (Pr E Heard) where she develops projects on the analysis of the molecular and phenotypic heterogeneity of breast carcinomas as well as collaborative studies with different members of Pr. E. Heard’s team on X chromosome reactivation in breast carcinomas (Chaligné et al Genome Biology, 2015).